Publications
Selected landmark and recent work
Explore publications spanning the discovery of human p53 isoforms, cell-fate control, cancer behaviour and clinical translation.
Germline variant affecting p53β isoforms predisposes to familial cancer
Nature Communications
Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas
eLife
It is not all about the alpha: elevated expression of p53β variants is associated with lower survival in melanoma
Cancer Cell International
Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage
Cell Death & Disease
Adaptive homeostasis and the p53 isoform network
EMBO Reports
p53 isoforms differentially impact on the POLι-dependent DNA damage tolerance pathway
Cell Death & Disease
Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumour immunity
Journal for ImmunoTherapy of Cancer
TP53 drives invasion through expression of its Δ133p53β variant
eLife
p53 Isoforms: Key Regulators of the Cell Fate Decision
Cold Spring Harbor Perspectives in Medicine
p53 isoforms through evolution: from identification to biological function
Cell Death & Differentiation
p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence
Nature Cell Biology
p53 isoforms can regulate p53 transcriptional activity
Genes & Development